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Lubica Chrastinova
Andrea Laukova
Monika Pogany Simonova
Maria Chrenkova
Zuzana Formelova
Jana Scerbova
Valentina Fockova
Maria Polacikova
Rudolf Zitnan
Lubomir Ondruska
Rastislav Jurcik


The aim of this study was to find: (1) whether bacteriocin-enterocin Ent A/P applied in rabbits drinking water can have an inhibitory effect on methicillin-resistant S. epidermidis P3/Tr2a; (2) whether application of the P3/Tr2a strain can negatively influence selected parameters and meat quality, and (3) if application of enterocin A/P can reduce possible negative impact of the P3/Tr2a strain. A total of 66 post-weaned hybrid rabbits (meat lines M91 and P91) of both sexes at the age of 35 days were divided into two experimental (EG1; EG2) and one control (CG) groups (22 rabbits in each group). Rabbits were kept in standard metal cages. They were fed with a mixture of a standard diet. At day 14, rabbits in the EG1 were administered with methicillin-resistant Staphylococcus epidermidis P3/Tr2a strain (in drinking water), marked with rifampicin (a dose of 500 μl/animal/day; 1.0 x 105 CFU/ml). Rabbits in the EG2 were administered with Ent A/P (50 μl/animal/day) supplied in drinking water (first 14 days). The rabbits had access to water ad libitum. Since day 22, all animals were fed only the untreated commercial granulated diet for growing rabbits. The experiment lasted for 48 days. Sampling of faecal mixtures per each group was provided at days 0/1, 14, 21 and 48 (end of experiment) to assess staphylococci and Staphylococcus epidermidis P3/Tr2a. At day 56 and at the end of the experiment, carcass and meat quality parameters (pH value 24 h post-mortem, colour lightness, water-holding capacity, protein and fat content, energetic value of the carcass yield) were measured. Methicillin-resistant SE strain did not affect negatively the selected physico-chemical parameters and nutritional quality of rabbit meat, as well as growth performance and the zootechnical parameters. In addition, in rabbits with Ent A/P, the highest daily weight gain was noted. In spite of the fact, that there was not significant reduction in the SE strain, enterocin A/P could be used as a preventive supplement in rabbit husbandry.

  • rabbits
  • meat quality
  • enterocin A/P
  • methicillin-resistance
  • Staphylococcus epidermidis P3/Tr2a
  • Article Details



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